So, What if I Call a Locksmith?

I do not have a safe, this is a completely theoretical question.

So say I inherit or buy "a safe." A generic safe. It is locked. I come here and you guys tell me to take it to a locksmith. OK.

So I call around. Do all or most locksmiths do this sort of thing? I drive the safe over to the shop and leave it there. What does the locksmith do? Manipulation? A master key? A call to the safe company? How long would it take to get my generic safe open? How much you figure I would end up paying?

"It depends" is probably correct, but unsatisfying.