Trail runners and sizing up?

Is it normal to size up for trail runners because of the socks? I bought my first pair of Brooks Cascadia 17’s and am wearing Injinji Cool Liners and regular midweight Darn toughs. My normal size is (EU) 39,5 but I tried on a 41 and it’s too small which means I have to size up 2 full sizes.

Is that normal? Thanks!

Edit: I also got some Altra Lone Peak 8’ and they feel a lot better on my feet without sizing up too much so guess it really just depends on the type of shoe :P