Feeling ‘sluggish’ after dosing

This post is mainly on behalf of my girlfriend.

We’ve made a nasal spray that delivers around 4-5mg of 2C-B per spray. We first started using 2C-B regularly in June, usually about every 2-3 weeks when we go out for a drink together.

The first nasal spray we made, from the original batch of 2C-B powder we bought, was great. During the come-up, we both felt a bit sluggish and “dead” for a short while, but then it shifted into pure euphoria and happiness.

Recently, we ran out of that first batch, so we purchased another gram of 2C-B and remade the nasal spray using this new powder. We tested it to confirm it’s actually 2C-B, and everything checked out.

Last week, we were excited to try out the new batch. We followed our usual routine—had a few drinks to get a little tipsy, then used the nasal spray. But this time, my girlfriend said she just felt sluggish and “dead” even 30-40 minutes after dosing, which never happened with the old batch. The new spray is the same concentration as before, about 4-5mg per spray, and I felt completely fine.

We tried it again this weekend. Once again, we had a few drinks, then used the spray. And once again, she felt drained and low-energy, while I felt energetic and euphoric. We redosed with another spray about 30 minutes later, which did increase the visuals as expected, but she still felt tired. She described it as missing the “MDMA-like” feeling she usually gets from 2C-B, while I had no issues feeling that.

Is there any possible explanation for this? We love sharing these experiences, but my girlfriend is hesitant to continue if it’s just going to make her feel tired and slow.